What causes high levels of vitamin B12 in blood?

May 23, 2020 Off By idswater

What causes high levels of vitamin B12 in blood?

Conditions that can increase B12 level include: Liver disease (such as cirrhosis or hepatitis) Myeloproliferative disorders (for example, polycythemia vera and chronic myelogenous leukemia)

What happens if your vitamin B12 level is high?

However, supplementing with excessively high levels of B12 has been linked to some negative side effects. Several studies have shown that megadoses of the vitamin can lead to outbreaks of acne and rosacea, a skin condition that causes redness and pus-filled bumps on the face.

Is B12 level of 1200 too high?

The normal range for vitamin B12 (total) is between 200 – 1100 ng/L (nanograms per liter), 200 – 1100 pg/mL (picograms per milliliter), or 148 – 811 pmol/L (picomoles per liter). The normal range for active vitamin B12 (holoTC) is around 20 – 134 pmol/L (picomoles per liter).

How long does it take to get rid of excess B12?

(See also Overview of Vitamins.) Unlike most other vitamins, B12 is stored in substantial amounts, mainly in the liver, until it is needed by the body. If a person stops consuming the vitamin, the body’s stores of this vitamin usually take about 3 to 5 years to exhaust.

Should I worry about high B12 levels?

There is no upper limit for vitamin B-12 intake because consuming high levels does not cause problems. However, having naturally high levels of vitamin B-12 in the body may be a cause for concern, as it suggests a severe underlying condition.

Should I be worried about high B12 levels?

What does it mean when B12 is high in your blood?

High B12 blood levels and diseases. Whilst low blood levels of vitamin B12 indicate deficiency in a test ; elevated blood levels are also often discovered. Figures above 900 pg/ml are considered high, but certain cases have recorded four or even five figure values.

What happens if you have too much vitamin B12?

Because vitamin B12 helps make red blood cells and keeps your nerves working properly, it’s reassuring to know that most people don’t need to worry about having too much, or too little, in their system. Consuming large amounts of the vitamin won’t make you sick. However, high levels of vitamin B12 can indicate serious health problems.

What are the symptoms of low B12 levels?

Your red blood cells contain a protein called hemoglobin, responsible for carrying oxygen throughout your body. In people with low B12 levels, weakness and fatigue are common symptoms. However, the opposite — high energy — is not a sign of high B12.

What kind of blood test to check vitamin B12?

This can be tested using a holo TC or MMA urine test , which only measure the usable B12 (holo TC) or the metabolic product (MMA test). High vitamin B12 blood levels which have not been caused by a mistimed test should always be followed up by an official B12 status check.

What does high B12 blood levels really mean?

High blood B12 levels can occur in liver conditions such as cirrhosis and hepatitis. Alcoholic liver disease is an example of a liver condition associated with high vitamin B12 . With alcoholic liver disease, vitamin B12 as well as its carrier proteins can be elevated.

What medical conditions cause high B12 levels?

High vitamin B12 in the bloodstream is associated with serious diseases. Medical conditions that can increase levels of vitamin B12 include liver disease, kidney failure and a group of blood cancers known as myeloproliferative disorders, which includes myelocytic leukemia and a condition that causes an overgrowth…

What are the side effects of too much vitamin B12?

That being said, too much vitamin B12 side effects can include diarrhea, itching, blood clots, numbness in the extremities, and severe allergic reactions. Excessive vitamin B12 may also increase the risk of prostate cancer. Some medications that may interact with vitamin B12 include anticonvulsants,…

What does an elevated B12 level mean?

Elevated levels of B12 can be caused by cirrhosis, scarring of the liver. Decreased liver function corresponds to elevated B12 levels because the liver cannot maintain B12 properly and the remainder is dispersed throughout the body.