Why is it important to study teratogens?

April 7, 2020 Off By idswater

Why is it important to study teratogens?

Geneticists specialize in the effects of teratogens on fetuses and can help you assess your actual risk given a specific exposure. You may also receive a targeted ultrasound evaluation to determine whether the fetus has been affected in some way.

Why do we study Teratology?

Introduction. Teratology is the study of birth defects, and its goals are (1) to describe and determine etiology, (2) to explore mechanisms involved in the production of birth defects and (3) to devise means of prevention.

What do teratogens include?

Teratogenic agents include infectious agents (rubella, cytomegalovirus, varicella, herpes simplex, toxoplasma, syphilis, etc.); physical agents (ionizing agents, hyperthermia); maternal health factors (diabetes, maternal PKU); environmental chemicals (organic mercury compounds, polychlorinated biphenyl or PCB.

What are the principles of Teratology?

In considering the effects of drugs on pregnancy, it is important to remember the 6 principles of teratology: genetic susceptibility, development stage, mechanisms, end points, access, and dose response.

What birth defects can teratogens cause?

During this time, teratogens can cause neural tube defects such as spina bifida. Some organs are sensitive to teratogens during the whole pregnancy. This includes the baby’s brain and spinal cord. Alcohol affects the brain and spinal cord, so it can cause harm at any time during pregnancy.

What is Teratology example?

Teratology, branch of the biological sciences dealing with the causes, development, description, and classification of congenital malformations in plants and animals and with the experimental production, in some instances, of these malformations.

What are the main causes of birth defects?

What causes birth defects?

  • Genetics. One or more genes might have a change or mutation that prevents them from working properly.
  • Chromosomal problems.
  • Exposures to medicines, chemicals, or other toxic substances.
  • Infections during pregnancy.
  • Lack of certain nutrients.

What is the most common teratogen to affect pregnancies?

Alcohol: One of the most commonly used teratogens is alcohol, and because half of all pregnancies in the United States are unplanned, it is recommended that women of child-bearing age take great caution against drinking alcohol when not using birth control or when pregnant (CDC, 2005).

Can teratogens cause birth defects?

As a baby grows in the womb, teratogens may affect parts of the baby’s body as they are forming. For example, the neural tube closes in the first 3 to 5 weeks of the pregnancy. During this time, teratogens can cause neural tube defects such as spina bifida.